Projects / Pharmaceutical water
Purified water below 1 µS/cm for Laboratorios LIFE
We designed, supplied, installed and commissioned a double-pass reverse osmosis system with electrodeionization (EDI) and automatic thermal sanitization, which produces purified water (PW) in accordance with the USP and WHO Technical Report 37.
- ClientLaboratorios LIFE
- Year2018
- IndustryPharmaceutical
- ScopeTurnkey project
Double-pass osmosis, EDI and UVPurified water (PW)
Project video
The Laboratorios LIFE project on video
Cristian Pinto, Sanitron’s projects director, walks through the installed system and explains how it works. Video in Spanish.
Continuous purified water for pharmaceutical production
LIFE needed to generate pharmaceutical-grade purified water without interruptions, from drinking water, and remove ionic, organic and bacteriological contaminants.
- Ionic purityConductivity below 1 µS/cm, under the USP limit of 1.3 µS/cm.
- Organics and bacteria under controlReduction of total organic carbon and thermal sanitization of the entire circuit.
- Continuous productionAutomatic operation based on tank level and online conductivity.
What each stage retainssystem barriers for each type of contaminant
Salts and organics pass through two barriers in series, and bacteria through three. Thermal sanitization acts on the entire circuit, not just the water.
- 108 m³/daydouble-pass reverse osmosis
- 96 m³/dayelectrodeionization
- 740 litersCIP tank for chemical cleaning
- < 1 µS/cmpurified water conductivity
Treatment train: from drinking water to purified water
Six stages with 316L stainless steel sanitary piping and automatic hot water sanitization (HSIP) for the system’s microbiological control.
- Polishing filterBag filter in a stainless steel housing that retains solids and protects the membranes.Retention above 1 µm
- Chemical dosingDiaphragm dosing pumps inject the chemicals that preserve the membranes.Control with ORP, pH and conductivity
- Heat exchangerTransfers heat during the system’s thermal sanitization (HSIP).316L stainless steel
- Double-pass reverse osmosisStainless steel high-pressure vertical pump and two-pass membranes that retain more than 99% of salts.108 m³/day
- Electrodeionization (EDI)Membranes and resins continuously regenerated by electric current polish the second-pass permeate.96 m³/day, < 1 µS/cm
- UV disinfection and TOC controlUV lamp on the product line that reduces TOC and complements microbiological control.On the product line
Automation and control
The PLC selects the operating mode based on tank level and online conductivity, and schedules thermal sanitization.
- ProductionThe tank calls for water and conductivity is within specification.
- RecirculationWater returns to the system and does not enter the tank until conductivity recovers.
- Stand-byWith the tank full, the system waits, ready to start.
- Thermal sanitizationThe exchanger heats the circuit and temperature sensors control the cycle.
- Online conductivity, pH and ORP
- Three-color tower with audible alarm
- Emergency stop on each skid
- Restart after power failures
Turnkey, from design to commissioning
Sanitron designed, supplied, installed and started up the complete system, and validated its thermal sanitization cycles.
What Sanitron did
- Engineering and designSizing of the purification train for PW water.
- SupplyPumps, polyethylene tanks, housings, instrumentation, membranes and EDI cells.
- InstallationElectromechanical installation, sanitary piping with minimal dead legs and panel wiring.
- CommissioningAutomatic operating routines, validation of HSIP thermal cycles and start-up.
Results
- Pharmaceutical-grade PW waterContinuous, automated and safe generation under international standards.
- Protected membranes and EDIChemical pretreatment controlled with online ORP, pH and conductivity.
- Fewer regeneration chemicalsContinuous EDI and automatic thermal sanitization reduce their use.
Does your pharmaceutical plant need PW purified water?
We design high-purity systems with EDI, thermal sanitization and precision automation, with local technical support.
Contact us
Office in EcuadorDe los Eucaliptos E8-70 y calle E9, Quito 170307
Phone+593 99 871 1330
+593 2 280 8126
Emailinfo@sanitronec.com
Office hoursMonday to Friday
9:00 a.m.–12:00 p.m. and 1:00–6:00 p.m.
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+1 786 972 2008